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VA/DoD Clinical Practice Guidelines

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Management of Hypertension (HTN) in Primary Care (2014)

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Addendum referencing SPRINT to the 2014 Hypertension CPG: Since publication of the 2014 VA-DoD Clinical Practice Guideline for the Management of Hypertension, the Systolic Blood Pressure Intervention Trial (SPRINT) was completed and published in 2015. The trial was stopped early, after a median follow-up of 3.26 years, when more intensive treatment (SBP target <120 mm Hg) resulted in a significant reduction in the primary composite outcome (25%), which included fatal and non-fatal cardiovascular disease, and a reduction in the secondary outcome of all-cause mortality (27%). SPRINT was conducted in 9,361 persons age ≥50 years with a SBP of 130-180 mm Hg (on or off antihypertensive medications) and an increased cardiovascular risk, but without diabetes, prior stroke, or dementia. SPRINT included approximately 2,000 veterans recruited from 28 VA medical centers (of 102 total clinical sites). The benefits were consistent across all prespecified subgroups, including... Read More

Cover page of the guideline document.The guideline describes the critical decision points in the Management of Hypertension in Primary Care and provides clear and comprehensive evidence based recommendations incorporating current information and practices for practitioners throughout the DoD and VA Health Care systems. The guideline is intended to improve patient outcomes and local management of patients with hypertension..

Disclaimer:This Clinical Practice Guideline is intended for use only as a tool to assist a clinician/healthcare professional and should not be used to replace clinical judgment.